10 of the Craziest, Longest Medical Terms to Ever Exist

(If you have Hippopomonstrosesquipedalophobia, this may not be for you. Or maybe it is, if you want to face your fears. If that’s the case, good luck!) 

Back when reading was THE top hobby, spotting and figuring out difficult words was pretty much a game in and of itself. This was true even for scientific papers and journals. It was in equal parts amusing and educational, particularly for knowledge-seeking readers. We’ve decided that just because we’re in the digital age doesn’t mean that we have to give up on discovering and learning new medical words, especially the lengthy, difficult ones.

In honor of the loveable nerds that came before us, we’ve compiled ten of the longest medical terms to have ever graced the English vocabulary.

(It’s okay. Take your time. Nothing to be ashamed of. We had a hard time reading them, too.)

1. Dimethylamidophenyldimethylpyrazolone

I know it’s just the first word but we might as well jump into the deep end. It’s currently the fourth longest word in the English dictionary and is the other term for Aminophenazone (Aminopyrine), an antipyretic and analgesic formerly widely used in rheumatism, neuritis, and common colds.

2. Esophagogastroduodenoscopy

EGD is a procedure wherein a small, flexible endoscope goes through the mouth and into the pharynx, esophagus, stomach, and duodenum. This process is done to allow doctors to see if there’s anything wrong with the digestive organs.

3. Hepaticocholangiocholecystenterostomies

This surgical term is considered to be the longest word in Gould’s Medical Dictionary. This procedure is done by creating a link or a bridge between a hepatic duct and the gall bladder and between the gall bladder and the intestine, allowing these organs to “communicate”. Who knew our organs could communicate?

4. Oligoasthenoteratozoospermia

This medical term is exclusively for male ears only, whether they like it or not . It is a condition wherein a man has a low sperm count resulting in a majority of sperm with poor morphology.

5. Uvulopalatopharyngoplasty

When you want to get rid of your snoring woes, you might want to consider this procedure. The surgeons will remove your tonsils and remodel the tissue in the region.

6. Arachibutyrophobia

This word is for the ridiculously specific phobia of having peanut butter stuck on the roof of the tongue. We’re both intrigued and saddened, to say the least.


The fear of long words. Huh. You don’t say.

8. Pseudopseudohypoparathyroidism

It’s a 30-letter thyroid disorder and is an inherited condition which causes short stature, round face, and short hand bones. Some people with this kind of condition also have learning disabilities. This term is usually abbreviated as PPHP, thank goodness.

9. Rhinotillexomania

This term is the medical name given to someone with obsessive nose picking that turns into OCD (Obsessive-Compulsive Disorder). Again, we are incredibly intrigued and saddened.

10. Pneumonoultramicroscopicsilicovolcanoconiosis

Yes, this is the big one – the longest word in the English dictionary. It is a lung disease which occurs when very fine ash and sand dust are inhaled. So don’t go snooping around volcanoes. You’ll probably give your doctors a hard time explaining your diagnosis with this 45-letter word.

You’ve done it! You reached the end of the article. We hope it made you feel supercalifragilisticexpialidocious. Got any other lengthy medical terms you think we missed?


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